Rapid <sup>18</sup>F-labeling <i>via</i> Pd-catalyzed <i>S</i>-arylation in aqueous medium
نویسندگان
چکیده
Rapid Pd-catalyzed S-arylation with easily accessible 2-[18F]fluoro-5-iodopyridine enables facile preparation of radiolabeled peptides and proteins.
منابع مشابه
Pd-catalyzed C3-selective arylation of pyridines with phenyl tosylates.
We have discovered that phenyl tosylates can be used to arylate pyridines at the C3-position using a Pd(OAc)2-1,10-phenanthroline catalyst system. We also discovered that the reaction of 4-methylpyridine with naphthyl tosylates occurred on the methyl group instead of at the C3-position.
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ژورنال
عنوان ژورنال: Chemical Communications
سال: 2021
ISSN: ['1359-7345', '1364-548X']
DOI: https://doi.org/10.1039/d1cc00745a